Research Paper Advance Articles

LncRNA RUSC1-AS1 promotes osteosarcoma progression through regulating the miR-340-5p and PI3K/AKT pathway

RUSC1-AS1 promoted osteosarcoma cell growth in vivo. (A) Tumor growth, (B) tumor weight and (C) tumor volume in U2OS injected nude mice treated with si-NC and si-RUSC1-AS1. (D) The protein expression of p-AKT, AKT, p-PI3K and PI3K in tumor cells from si-NC or si-RUSC1-AS1 treated mice. (E) The expression of EMT-related genes in mice treated with si-NC and si-RUSC1-AS1.

Figure 7. RUSC1-AS1 promoted osteosarcoma cell growth in vivo. (A) Tumor growth, (B) tumor weight and (C) tumor volume in U2OS injected nude mice treated with si-NC and si-RUSC1-AS1. (D) The protein expression of p-AKT, AKT, p-PI3K and PI3K in tumor cells from si-NC or si-RUSC1-AS1 treated mice. (E) The expression of EMT-related genes in mice treated with si-NC and si-RUSC1-AS1.