Figure 1. LncRNA HCP5 is overexpressed in HCC tissues and cell lines. (A) The expression level of HCP5 in HCC tissues is significantly higher compared to that in paracancerous tissues (***p<0.001, GAPDH used served as the internal control). (B) HCP5 is overexpressed in HCC cell lines (***p<0.001, **p<0.01), and the expression level is low in normal hepatocytes. (C) The expression of HCP5 in tumors with a size >5 cm, migrated HCC tissues, recurrent cancer tissues, and high histological grade tumor tissues was significantly higher (**p<0.01, ***p<0.001). (D) FISH assay indicating that HCP5 was predominantly localized in the cytoplasm of Hep3B cell lines.