COVID-19 Research Paper Volume 13, Issue 12 pp 15770—15784

In silico analysis identifies neuropilin-1 as a potential therapeutic target for SARS-Cov-2 infected lung cancer patients

Correlation analysis between NRP1/TMPRSS2 and pro-tumorigenic factors. (A) Correlation analysis between NRP1 and markers for CAFs and M2 macrophage in LUSC (n=501) and LUAD (n=515). (B) Correlation analysis between TMPRSS2 and markers for CAFs and M2 macrophage in LUSC and LUAD. (C) Correlation analysis between NRP1 and MMP1, MMP3, MMP9, VEGFC, FLT4 and CXCL12 in LUSC and LUAD. (D) Correlation analysis between TMPRSS2 and MMP1, MMP3, MMP9, VEGFC, FLT4 and CXCL12 in LUSC and LUAD. None purity-adjusted for all the panels.

Figure 5. Correlation analysis between NRP1/TMPRSS2 and pro-tumorigenic factors. (A) Correlation analysis between NRP1 and markers for CAFs and M2 macrophage in LUSC (n=501) and LUAD (n=515). (B) Correlation analysis between TMPRSS2 and markers for CAFs and M2 macrophage in LUSC and LUAD. (C) Correlation analysis between NRP1 and MMP1, MMP3, MMP9, VEGFC, FLT4 and CXCL12 in LUSC and LUAD. (D) Correlation analysis between TMPRSS2 and MMP1, MMP3, MMP9, VEGFC, FLT4 and CXCL12 in LUSC and LUAD. None purity-adjusted for all the panels.