Research Paper Volume 13, Issue 12 pp 16425—16444

Selected using bioinformatics and molecular docking analyses, PHA-793887 is effective against osteosarcoma

Anti-osteosarcoma effects of PHA-793887. (A) Cellular viability of osteosarcoma cells treated with PHA-793887. (B) Colony formation assay results demonstrating the anti-proliferative effects of PHA-793887 in MG63 and U20S cells. (C) Scratch assay results demonstrating that PHA-793887 suppressed the migration of osteosarcoma cells. (D) Numbers of clones formed by MG64 and U20S cells. (E) Images from the wound-healing assay, representing the migration capacity of osteosarcoma cells. (F) Apoptosis of osteosarcoma cells treated with PHA-793887.

Figure 5. Anti-osteosarcoma effects of PHA-793887. (A) Cellular viability of osteosarcoma cells treated with PHA-793887. (B) Colony formation assay results demonstrating the anti-proliferative effects of PHA-793887 in MG63 and U20S cells. (C) Scratch assay results demonstrating that PHA-793887 suppressed the migration of osteosarcoma cells. (D) Numbers of clones formed by MG64 and U20S cells. (E) Images from the wound-healing assay, representing the migration capacity of osteosarcoma cells. (F) Apoptosis of osteosarcoma cells treated with PHA-793887.