Research Paper Volume 13, Issue 11 pp 14843—14861

TP73-AS1 is induced by YY1 during TMZ treatment and highly expressed in the aging brain

TP73-AS1 is highly expressed in the pathological aging brain. (A) The levels of TP73-AS1 in Alzheimer’s (AD) vs. normal brain are shown. Data were obtained from R2 and the Cotman dataset (GSE48350). In both (A, B) panels, asterisks indicate statistically significant differences as calculated by the two-sample Wilcoxon test (*p B) The levels of TP73-AS1 in Alzheimer’s vs. normal brain are shown. Data were obtained from R2 and the Salomon dataset (GSE5281).

Figure 2. TP73-AS1 is highly expressed in the pathological aging brain. (A) The levels of TP73-AS1 in Alzheimer’s (AD) vs. normal brain are shown. Data were obtained from R2 and the Cotman dataset (GSE48350). In both (A, B) panels, asterisks indicate statistically significant differences as calculated by the two-sample Wilcoxon test (*p < 0.05; NS, non-significant). (B) The levels of TP73-AS1 in Alzheimer’s vs. normal brain are shown. Data were obtained from R2 and the Salomon dataset (GSE5281).