Research Paper Volume 13, Issue 12 pp 16667—16683

Correlation of IL-6 and JAK2/STAT3 signaling pathway with prognosis of nasopharyngeal carcinoma patients

The positive rates of IL-6, STAT3, p-STAT3, JAK2, p-JAK2 and CyclinD1 were obviously higher in NPC tissues. (A) The results of immunohistochemical staining in NPC tissues and normal nasopharyngeal epithelial tissues (× 400); (B) The positive expression rates of IL-6, STAT3, p-STAT3, JAK2, p-JAK2 and CyclinD1 in NPC tissues (n = 117) and normal nasopharyngeal epithelial tissues (n = 112) (5 sections selected in each result); *p

Figure 1. The positive rates of IL-6, STAT3, p-STAT3, JAK2, p-JAK2 and CyclinD1 were obviously higher in NPC tissues. (A) The results of immunohistochemical staining in NPC tissues and normal nasopharyngeal epithelial tissues (× 400); (B) The positive expression rates of IL-6, STAT3, p-STAT3, JAK2, p-JAK2 and CyclinD1 in NPC tissues (n = 117) and normal nasopharyngeal epithelial tissues (n = 112) (5 sections selected in each result); *p < 0.05 when vs. normal nasopharyngeal epithelial tissues. Abbreviation: NPC: nasopharyngeal carcinoma.