Research Paper Volume 13, Issue 12 pp 16667—16683

Correlation of IL-6 and JAK2/STAT3 signaling pathway with prognosis of nasopharyngeal carcinoma patients

IL-6 enhances NPC cell migration and invasion in vitro. (A) Cell migration of CNE-1 cells (×40); (B) Migration distance of CNE-1 cells; (C) Cell invasion of SUNE-1 cells (×40); (D) Migration distance of SUNE1 cells; (E) Cell invasion of CNE-1 cells (×200); (F) The number of invasive CNE-1 cells; (G) Cell invasion of SUNE1 cells (×200); (H) The number of invasive SUNE1 cells. *p #p

Figure 6. IL-6 enhances NPC cell migration and invasion in vitro. (A) Cell migration of CNE-1 cells (×40); (B) Migration distance of CNE-1 cells; (C) Cell invasion of SUNE-1 cells (×40); (D) Migration distance of SUNE1 cells; (E) Cell invasion of CNE-1 cells (×200); (F) The number of invasive CNE-1 cells; (G) Cell invasion of SUNE1 cells (×200); (H) The number of invasive SUNE1 cells. *p < 0.05 vs. the blank group; #p < 0.05 vs. the IL-6 + AG490 group. The experiment in each group was repeated three times. Abbreviations: NC: negative control; IL-6: interleukin-6; NPC: nasopharyngeal carcinoma.