Research Paper Volume 13, Issue 13 pp 17227—17236

miR-let-7c-5p and miR-149-5p inhibit proinflammatory cytokine production in osteoarthritis and rheumatoid arthritis synovial fibroblasts

Anti-inflammatory agents upregulate miR-let-7c-5p and miR-149-5p expression. OASFs (A–C) and RASFs (D–F) were treated with dexamethasone, celecoxib, or indomethacin (1–50 μM), then subjected to qPCR quantification of miR-let-7c-5p and miR-149-5p expression.

Figure 4. Anti-inflammatory agents upregulate miR-let-7c-5p and miR-149-5p expression. OASFs (AC) and RASFs (DF) were treated with dexamethasone, celecoxib, or indomethacin (1–50 μM), then subjected to qPCR quantification of miR-let-7c-5p and miR-149-5p expression.