Research Paper Volume 13, Issue 13 pp 17285—17301

Knockdown of lncRNA ZNRD1-AS1 suppresses gastric cancer cell proliferation and metastasis by targeting the miR-9-5p/HSP90AA1 axis

ZNRD1-AS1 knockdown suppresses tumor growth and pulmonary metastasis in a nude mouse model. (A) Micrographs of subcutaneous tumors formed by MGC803 and BGC823 cells of the shZNRD1-AS1 and NC groups. (B) Growth curves of subcutaneous tumors formed by MGC803 and BGC823 cells of the shZNRD1-AS1 or NC groups. (C) Metastasis in the lungs of nude mice intravenously injected with MGC803 and BGC823 cells from the shZNRD1-AS1 or NC groups. Left panels show representative micrographs. The right panel is a graph of mean metastatic loci.

Figure 7. ZNRD1-AS1 knockdown suppresses tumor growth and pulmonary metastasis in a nude mouse model. (A) Micrographs of subcutaneous tumors formed by MGC803 and BGC823 cells of the shZNRD1-AS1 and NC groups. (B) Growth curves of subcutaneous tumors formed by MGC803 and BGC823 cells of the shZNRD1-AS1 or NC groups. (C) Metastasis in the lungs of nude mice intravenously injected with MGC803 and BGC823 cells from the shZNRD1-AS1 or NC groups. Left panels show representative micrographs. The right panel is a graph of mean metastatic loci.