Figure 2. PDS alters the structure of chromatin and cytoplasm in primary neurons, astrocytes, and microglia. Representative electron micrographs of cultured cortical neurons, astrocytes, and microglia treated with a vehicle overnight (left panel) and with 2 μM PDS overnight (right panel). Bar (neuronal cells), 1 μm; bar (astrocytes and microglia), 2 μm. Primary cultures were fixed and processed for electron microscopy imaging. Results were pooled from two independent experiments.