Figure 6. Effects of combination treatment with RAPA and SAHA on A549 xenografts model after receiving IR. (A) Bodyweight in A549 cell xenografts measured every 4 days. (B, C) Specimens and tumor weight of A549 cell xenograft after different treatments for 28 days. (D) Tumor volume of A549 cell xenograft in nude mice measured every 4 days. (E) Immunohistochemical staining of γ-H2AX, LC3 and Ac-H3 in A549 cell xenografts (×200).