Research Paper Volume 13, Issue 13 pp 17489—17498

HDAC inhibitor Trichostatin A suppresses adipogenesis in 3T3-L1 preadipocytes

The effects of TSA on cell viability of 3T3-L1 cells. Cells were stimulated with 0.1, 0.25, 0.5, 1, 2.5, and 5 μM TSA for 4 days and 8 days. (A) Cell viability was determined using an MTT on day 4; (B) Cell viability was determined with MTT on day 8 (n= 5-6, *, **, ***, P

Figure 1. The effects of TSA on cell viability of 3T3-L1 cells. Cells were stimulated with 0.1, 0.25, 0.5, 1, 2.5, and 5 μM TSA for 4 days and 8 days. (A) Cell viability was determined using an MTT on day 4; (B) Cell viability was determined with MTT on day 8 (n= 5-6, *, **, ***, P<0.05, 0.01, 0.001 vs. vehicle group).