Research Paper Volume 13, Issue 13 pp 17499—17515

Downregulation of LINC00665 suppresses the progression of lung adenocarcinoma via regulating miR-181c-5p/ZIC2 axis

Evaluation of the expression levels of LINC00665, miR-181c-5p, ZIC2, HOXA1 and HOXA11 in LUAD tissues and their clinical values. (A–E) The expression of LINC00665, miR-181c-5p, ZIC2, HOXA1 and HOXA11 in 84 paired LUAD tissues and the paracancerous normal tissues were tested by RT-PCR technology. (F–J) Overall survival analysis of the effects of different expression levels of LINC00665, miR-181c-5p, ZIC2, HOXA1 and HOXA11 in the prognosis of LUAD patients. (K–O) Pearson correlation analysis of the correlations between LINC00665, ZIC2, miR-181c-5p, HOXA1 and HOXA11. (*p

Figure 4. Evaluation of the expression levels of LINC00665, miR-181c-5p, ZIC2, HOXA1 and HOXA11 in LUAD tissues and their clinical values. (AE) The expression of LINC00665, miR-181c-5p, ZIC2, HOXA1 and HOXA11 in 84 paired LUAD tissues and the paracancerous normal tissues were tested by RT-PCR technology. (FJ) Overall survival analysis of the effects of different expression levels of LINC00665, miR-181c-5p, ZIC2, HOXA1 and HOXA11 in the prognosis of LUAD patients. (KO) Pearson correlation analysis of the correlations between LINC00665, ZIC2, miR-181c-5p, HOXA1 and HOXA11. (*p<0.05).