Research Paper Volume 13, Issue 15 pp 19260—19271

Downregulation of lncRNA SBF2-AS1 inhibits hepatocellular carcinoma proliferation and migration by regulating the miR-361-5p/TGF-β1 signaling pathway

Effect of lncRNA SBF2-AS1 on miR-361-5p. (A) Prediction of a connection site of lncRNA SBF2-AS1 and miR-361-5p. (B) The influence of si-SBF2-AS1 on lncRNA SBF2-AS1 in HepG2 cells. (C) The influence of si-SBF2-AS1 on lncRNA SBF2-AS1 in Hep3B cells. (D) The effect of lncRNA SBF2-AS1 downregulation on miR-361-5p in HepG2 cells. (E) The influence of lncRNA SBF2-AS1 downregulation on miR-361-5p in Hep3B cells. The obtained data are expressed as mean ± SEM. * P

Figure 2. Effect of lncRNA SBF2-AS1 on miR-361-5p. (A) Prediction of a connection site of lncRNA SBF2-AS1 and miR-361-5p. (B) The influence of si-SBF2-AS1 on lncRNA SBF2-AS1 in HepG2 cells. (C) The influence of si-SBF2-AS1 on lncRNA SBF2-AS1 in Hep3B cells. (D) The effect of lncRNA SBF2-AS1 downregulation on miR-361-5p in HepG2 cells. (E) The influence of lncRNA SBF2-AS1 downregulation on miR-361-5p in Hep3B cells. The obtained data are expressed as mean ± SEM. * P < 0.05, ** P < 0.01 vs. si-NC; n=3.