Research Paper Volume 13, Issue 15 pp 19260—19271

Downregulation of lncRNA SBF2-AS1 inhibits hepatocellular carcinoma proliferation and migration by regulating the miR-361-5p/TGF-β1 signaling pathway

Suppression of miR-361-5p attenuates the influence of lncRNA SBF2-AS1 downregulation on the viability of HCC cells. (A) The cell viability of HepG2 cells. (B) The cell viability of Hep3B cells. (C) The mRNA expression of TGF-β1 in HepG2 cells. (D) The level of TGF-β1 mRNA in Hep3B cells. (E) The level of TGF-β1 protein in HepG2 cells. (F) The level of TGF-β1 protein in Hep3B cells. The obtained data are expressed as mean ± SEM. ** P

Figure 4. Suppression of miR-361-5p attenuates the influence of lncRNA SBF2-AS1 downregulation on the viability of HCC cells. (A) The cell viability of HepG2 cells. (B) The cell viability of Hep3B cells. (C) The mRNA expression of TGF-β1 in HepG2 cells. (D) The level of TGF-β1 mRNA in Hep3B cells. (E) The level of TGF-β1 protein in HepG2 cells. (F) The level of TGF-β1 protein in Hep3B cells. The obtained data are expressed as mean ± SEM. ** P < 0.05 vs. si-NC+AMO-NC; # P < 0.05, ## P < 0.01 vs. si-SBF2-AS1+ AMO-NC; n=3.