Research Paper Volume 13, Issue 15 pp 19260—19271

Downregulation of lncRNA SBF2-AS1 inhibits hepatocellular carcinoma proliferation and migration by regulating the miR-361-5p/TGF-β1 signaling pathway

Suppression of miR-361-5p attenuates the influence of lncRNA SBF2-AS1 downregulation on the migration of HCC cells. (A) Representative images of HepG2 and Hep3B cells. (B) Migration distance of HepG2 cells. (C) Cell migration distance of Hep3B cells. (D) Representative BCCMY images of HepG2 and Hep3B cells. (E) The number of migrating HepG2 cells. (F) The number of migrating HepG2 cells. *** P A–C), n=6; (D–F), n=3.

Figure 6. Suppression of miR-361-5p attenuates the influence of lncRNA SBF2-AS1 downregulation on the migration of HCC cells. (A) Representative images of HepG2 and Hep3B cells. (B) Migration distance of HepG2 cells. (C) Cell migration distance of Hep3B cells. (D) Representative BCCMY images of HepG2 and Hep3B cells. (E) The number of migrating HepG2 cells. (F) The number of migrating HepG2 cells. *** P < 0.001 vs. si-NC+AMO-NC; ### P < 0.001 vs. si-SBF2-AS1+ AMO-NC; (AC), n=6; (DF), n=3.