Research Paper Volume 13, Issue 13 pp 17592—17606

DNA methylation biomarkers for diagnosis of primary liver cancer and distinguishing hepatocellular carcinoma from intrahepatic cholangiocarcinoma

Distribution of differentially methylated sites and genes in HCC and ICC. Distribution of differentially methylated sites according to CpG island location in HCC (A) and ICC (E). Distribution of differentially methylated genes according to CpG island location in HCC (B) and ICC (F). Distribution of differentially methylated sites according to the distance to the TSS in HCC (C) and ICC (G). Distribution of differentially methylated genes according to the distance to the TSS in HCC (D) and ICC (H).

Figure 1. Distribution of differentially methylated sites and genes in HCC and ICC. Distribution of differentially methylated sites according to CpG island location in HCC (A) and ICC (E). Distribution of differentially methylated genes according to CpG island location in HCC (B) and ICC (F). Distribution of differentially methylated sites according to the distance to the TSS in HCC (C) and ICC (G). Distribution of differentially methylated genes according to the distance to the TSS in HCC (D) and ICC (H).