Research Paper Volume 13, Issue 17 pp 21090—21101

Effect of the Notch1-mediated PI3K-Akt-mTOR pathway in human osteosarcoma

shNotch1 induced osteosarcoma cell apoptosis and cell proliferation. (A) shNotch1 treatment induced up-regulated osteosarcoma cell apoptosis. (B) shNotch1 treatment induced up-regulated osteosarcoma cell colony formation.

Figure 4. shNotch1 induced osteosarcoma cell apoptosis and cell proliferation. (A) shNotch1 treatment induced up-regulated osteosarcoma cell apoptosis. (B) shNotch1 treatment induced up-regulated osteosarcoma cell colony formation.