Research Paper Volume 13, Issue 15 pp 19306—19316

LncRNA-HAGLR motivates triple negative breast cancer progression by regulation of WNT2 via sponging miR-335-3p

HAGLR promoted TNBC growth in vivo. 30 mice were divided into two group randomly, BT549 cells was subcutaneously injected into nude mice. 1 week later, we injected lentivirus packaged HAGLR or NC into tumors. (A) Tumor volume was measured every 7 days. (B) Tumors was isolated after 28 days of BT549 cells injection, and photos for representative tumors. (C) The mRNA of HAGLR, miR-335-3p, and WNT2 in isolated tumors were detected by qRT-PCR. Data are mean ± SD; *P

Figure 6. HAGLR promoted TNBC growth in vivo. 30 mice were divided into two group randomly, BT549 cells was subcutaneously injected into nude mice. 1 week later, we injected lentivirus packaged HAGLR or NC into tumors. (A) Tumor volume was measured every 7 days. (B) Tumors was isolated after 28 days of BT549 cells injection, and photos for representative tumors. (C) The mRNA of HAGLR, miR-335-3p, and WNT2 in isolated tumors were detected by qRT-PCR. Data are mean ± SD; *P < 0.05.