Research Paper Volume 13, Issue 14 pp 18298—18309

NUDCD1 knockdown inhibits the proliferation, migration, and invasion of pancreatic cancer via the EMT process

Expression and roles of NUDCD1 in PC. (A) NUDCD1 mRNA expression levels were significantly higher in PDAC tissues (n = 179) than in normal pancreatic tissues (n = 171). (B, C) NUDCD1 upregulation was significantly correlated with shorter overall survival and shorter disease-free survival (p = 0.041 and 0.037, respectively). (D) NUDCD1 was overexpressed in PDAC tissues relative to adjacent tissues as detected by IHC. (E) NUDCD1 upregulation was observed in different PC cell lines by qRT-PCR. (F, G) High NUDCD1 expression was observed in different PC cell lines by Western blot. *p

Figure 1. Expression and roles of NUDCD1 in PC. (A) NUDCD1 mRNA expression levels were significantly higher in PDAC tissues (n = 179) than in normal pancreatic tissues (n = 171). (B, C) NUDCD1 upregulation was significantly correlated with shorter overall survival and shorter disease-free survival (p = 0.041 and 0.037, respectively). (D) NUDCD1 was overexpressed in PDAC tissues relative to adjacent tissues as detected by IHC. (E) NUDCD1 upregulation was observed in different PC cell lines by qRT-PCR. (F, G) High NUDCD1 expression was observed in different PC cell lines by Western blot. *p<0.05, **p<0.01, ***p<0.001, ****p<0.0001.