Figure 3. NUDCD1 knockdown induced the apoptosis of PC cells. (A–D) Flow cytometric analysis revealed that NUDCD1 knockdown increased the rate of apoptosis in Patu8988 and PANC-1 cells. (E–N) Western blot analysis showed that NUDCD1 knockdown decreased the expression of Bcl-2 and increased the expression of Bax and Cleaved Caspase-3 in PANC-1 and Patu8988 cells. **p<0.01, ***p<0.001, ****p<0.0001.