Research Paper Volume 13, Issue 14 pp 18298—18309

NUDCD1 knockdown inhibits the proliferation, migration, and invasion of pancreatic cancer via the EMT process

NUDCD1 knockdown induced the apoptosis of PC cells. (A–D) Flow cytometric analysis revealed that NUDCD1 knockdown increased the rate of apoptosis in Patu8988 and PANC-1 cells. (E–N) Western blot analysis showed that NUDCD1 knockdown decreased the expression of Bcl-2 and increased the expression of Bax and Cleaved Caspase-3 in PANC-1 and Patu8988 cells. **p

Figure 3. NUDCD1 knockdown induced the apoptosis of PC cells. (AD) Flow cytometric analysis revealed that NUDCD1 knockdown increased the rate of apoptosis in Patu8988 and PANC-1 cells. (EN) Western blot analysis showed that NUDCD1 knockdown decreased the expression of Bcl-2 and increased the expression of Bax and Cleaved Caspase-3 in PANC-1 and Patu8988 cells. **p<0.01, ***p<0.001, ****p<0.0001.