Research Paper Advance Articles

Agomelatine prevents angiotensin II-induced endothelial and mononuclear cell adhesion

Agomelatine reduced Ang II-induced expression of Egr-1 in HUVECs. HUVECs were treated with Ang II (1 μM) with or without agomelatine (10, 20 μM) for 24 h. mRNA of Egr-1 (##, **, &&, P

Figure 6. Agomelatine reduced Ang II-induced expression of Egr-1 in HUVECs. HUVECs were treated with Ang II (1 μM) with or without agomelatine (10, 20 μM) for 24 h. mRNA of Egr-1 (##, **, &&, P<0.01 vs. vehicle control, Ang II, Ang II+ 10 μM agomelatine group).