Research Paper Volume 13, Issue 14 pp 18740—18756

MicroRNA-106b-5p inhibits growth and progression of lung adenocarcinoma cells by downregulating IGSF10

IGSF10 expression is downregulated in several cancers including LUAD. (A) Oncomine database analysis shows expression levels of IGSF10 in several cancer types. Blue represents low expression of IGSF10 in tumor tissues compared to the corresponding normal tissues; the numbers correspond to the datasets for each cancer type. (B) IGSF10 expression levels in LUAD and normal lung cancer samples in the GSE19188 dataset. (C) IGSF10 expression levels in LUSC and normal lung tissue samples in the GSE19188 dataset. (D) IGSF10 expression levels in LUAD and normal lung tissue samples in the GSE31210 dataset. (E) IGSF10 expression levels in LUAD and normal lung tissue samples in the GSE32863 dataset.

Figure 1. IGSF10 expression is downregulated in several cancers including LUAD. (A) Oncomine database analysis shows expression levels of IGSF10 in several cancer types. Blue represents low expression of IGSF10 in tumor tissues compared to the corresponding normal tissues; the numbers correspond to the datasets for each cancer type. (B) IGSF10 expression levels in LUAD and normal lung cancer samples in the GSE19188 dataset. (C) IGSF10 expression levels in LUSC and normal lung tissue samples in the GSE19188 dataset. (D) IGSF10 expression levels in LUAD and normal lung tissue samples in the GSE31210 dataset. (E) IGSF10 expression levels in LUAD and normal lung tissue samples in the GSE32863 dataset.