Research Paper Volume 13, Issue 14 pp 18740—18756

MicroRNA-106b-5p inhibits growth and progression of lung adenocarcinoma cells by downregulating IGSF10

Prognostic significance of IGSF10 expression levels in TCGA-LUAD dataset and clinical subgroups. (A) Kaplan-Meier survival curve analysis shows overall survival (OS) rates of TCGA-LUAD dataset patients with high- and low- IGSF10 expression levels. (B) Kaplan-Meier survival curve analysis shows overall survival (OS) rates of female LUAD patients with high- and low-IGSF10 expression. (C) Kaplan-Meier survival curve analysis shows overall survival (OS) rates of male LUAD patients with high- and low-IGSF10 expression. (D) Kaplan-Meier survival curve analysis shows overall survival (OS) rates in non-smoker group LUAD patients with high- and low-IGSF10 expression. (E) Kaplan-Meier survival curve analysis shows overall survival (OS) rates of smoker group LUAD patients with high- and low-IGSF10 expression. (F) Spearman’s correlation analysis shows association between IGSF10 expression and smoking in LUAD patients from non-smoker and smoker subgroups.

Figure 2. Prognostic significance of IGSF10 expression levels in TCGA-LUAD dataset and clinical subgroups. (A) Kaplan-Meier survival curve analysis shows overall survival (OS) rates of TCGA-LUAD dataset patients with high- and low- IGSF10 expression levels. (B) Kaplan-Meier survival curve analysis shows overall survival (OS) rates of female LUAD patients with high- and low-IGSF10 expression. (C) Kaplan-Meier survival curve analysis shows overall survival (OS) rates of male LUAD patients with high- and low-IGSF10 expression. (D) Kaplan-Meier survival curve analysis shows overall survival (OS) rates in non-smoker group LUAD patients with high- and low-IGSF10 expression. (E) Kaplan-Meier survival curve analysis shows overall survival (OS) rates of smoker group LUAD patients with high- and low-IGSF10 expression. (F) Spearman’s correlation analysis shows association between IGSF10 expression and smoking in LUAD patients from non-smoker and smoker subgroups.