Research Paper Volume 13, Issue 14 pp 18740—18756

MicroRNA-106b-5p inhibits growth and progression of lung adenocarcinoma cells by downregulating IGSF10

Identification of differentially expressed mRNAs and miRNAs in LUAD tissues and their functional enrichment analysis. (A) Volcano map shows differentially expressed mRNAs (DEG- mRNAs) in the TCGA-LUAD dataset. (B) Volcano map shows differentially expressed miRNAs (DEG- miRNAs) in the TCGA-LUAD dataset. (C) Heat map shows expression levels of DEG- mRNAs in TCGA-LUAD dataset. (D) Heat map shows expression levels of DEG- miRNAs in TCGA-LUAD dataset. (E) KEGG pathway analysis of DEG- mRNAs shows the top 12 upregulated pathways in LUAD tissues of the TCGA dataset. (F) Gene ontology analysis of DEG-mRNAs shows the top 12 biological processes in LUAD tissues of the TCGA dataset.

Figure 7. Identification of differentially expressed mRNAs and miRNAs in LUAD tissues and their functional enrichment analysis. (A) Volcano map shows differentially expressed mRNAs (DEG- mRNAs) in the TCGA-LUAD dataset. (B) Volcano map shows differentially expressed miRNAs (DEG- miRNAs) in the TCGA-LUAD dataset. (C) Heat map shows expression levels of DEG- mRNAs in TCGA-LUAD dataset. (D) Heat map shows expression levels of DEG- miRNAs in TCGA-LUAD dataset. (E) KEGG pathway analysis of DEG- mRNAs shows the top 12 upregulated pathways in LUAD tissues of the TCGA dataset. (F) Gene ontology analysis of DEG-mRNAs shows the top 12 biological processes in LUAD tissues of the TCGA dataset.