Research Paper Volume 13, Issue 14 pp 19028—19047

Development and validation of prognostic model based on the analysis of autophagy-related genes in colon cancer

Assessment of the immune-/chemotherapeutic response in the different risk-groups. (A) PDCD1, (B) HAVCR2, (C) CTLA4, (D) CD8A, (E) CXCL9, (F) LAG3, (G) TBX2, and (H) PRF1 expression between the different risk-groups and correlation between their expression and risk score. The risk score was negatively correlated with the IC50 of chemotherapeutics, including (I) cisplatin, (J) doxorubicin, and (K) paclitaxel; *p

Figure 11. Assessment of the immune-/chemotherapeutic response in the different risk-groups. (A) PDCD1, (B) HAVCR2, (C) CTLA4, (D) CD8A, (E) CXCL9, (F) LAG3, (G) TBX2, and (H) PRF1 expression between the different risk-groups and correlation between their expression and risk score. The risk score was negatively correlated with the IC50 of chemotherapeutics, including (I) cisplatin, (J) doxorubicin, and (K) paclitaxel; *p < 0.05; **p < 0.01; ***p < 0.001.