Research Paper Volume 13, Issue 15 pp 19587—19597

LncRNA AC136007.2 alleviates cerebral ischemic-reperfusion injury by suppressing autophagy

Overexpression of AC136007.2 decreases OGD/R-induced apoptosis and inflammatory cytokine release in SH-SY5Y cells. (A) Cell apoptosis was analyzed by flow cytometry after Annexin V/PI double staining. (B) Quantification of apoptosis rates from experiments like those shown in (A). (C–E) ELISA analysis of pro-inflammatory cytokine levels in cell culture supernatants. **p## p

Figure 2. Overexpression of AC136007.2 decreases OGD/R-induced apoptosis and inflammatory cytokine release in SH-SY5Y cells. (A) Cell apoptosis was analyzed by flow cytometry after Annexin V/PI double staining. (B) Quantification of apoptosis rates from experiments like those shown in (A). (CE) ELISA analysis of pro-inflammatory cytokine levels in cell culture supernatants. **p<0.01 versus control group; ## p<0.01 versus OGD/R group; n = 3.