Research Paper Volume 13, Issue 15 pp 19678—19695

Identification of inflammation-related DNA methylation biomarkers in periodontitis patients based on weighted co-expression analysis

The translational disorders in the periodontitis were related to immunity and epigenetic inheritance. (A) Differences between four immune-related pathways significantly enriched by GSEA in periodontitis and normal samples. (B) Expression of EZH2 in periodontitis and normal samples. (C) Expression of DNMT1 in periodontitis and normal samples. (D) Expression of DNMT3A in periodontitis and normal samples. (E) Expression of DNMT3B in periodontitis and normal samples. *p**p***p****p

Figure 1. The translational disorders in the periodontitis were related to immunity and epigenetic inheritance. (A) Differences between four immune-related pathways significantly enriched by GSEA in periodontitis and normal samples. (B) Expression of EZH2 in periodontitis and normal samples. (C) Expression of DNMT1 in periodontitis and normal samples. (D) Expression of DNMT3A in periodontitis and normal samples. (E) Expression of DNMT3B in periodontitis and normal samples. *p<0.05, **p<0.01, ***p<0.001 and ****p<0.0001.