Research Paper Volume 13, Issue 15 pp 19678—19695

Identification of inflammation-related DNA methylation biomarkers in periodontitis patients based on weighted co-expression analysis

Genomic characteristics of immune-related co-DMPs. (A) The methylation distribution of 23 co-DMPs in patients and healthy groups. (B) The 20 immune genes annotated by 23 co-DMPs were differentially expressed in patients and healthy groups. (C) Hypermethylated and unmethylated distributions of 23 co-DMPs in each sample. (D) Distribution of 13 potential disease-specific markers in the promoter region.

Figure 4. Genomic characteristics of immune-related co-DMPs. (A) The methylation distribution of 23 co-DMPs in patients and healthy groups. (B) The 20 immune genes annotated by 23 co-DMPs were differentially expressed in patients and healthy groups. (C) Hypermethylated and unmethylated distributions of 23 co-DMPs in each sample. (D) Distribution of 13 potential disease-specific markers in the promoter region.