Research Paper Volume 13, Issue 15 pp 19776—19788

Exosomal lncRNA LINC01711 facilitates metastasis of esophageal squamous cell carcinoma via the miR-326/FSCN1 axis

Interference with the expression of LINC01711 inhibited the proliferation, migration and invasion of TE-1 cells and promoted apoptosis. (A) RT-qPCR was used to test the interference efficiency of LINC01711 sh-RNA on TE-1 cells. n=6. (B) The proliferation of TE-1 cells was detected by EdU method. n=6. (C) Colony forming ability was determined by colony formation test. n=6. (D) The apoptosis of TE-1 cells was detected by flow cytometry. (E) The migration of TE-1 cells was detected by wound healing assay. n=6. (F) The invasiveness of TE-1 cells was detected by Transwell method. n=6. (G) Representative tumor images. (H) Tumor volume growth curve of each group, n=5. p p

Figure 2. Interference with the expression of LINC01711 inhibited the proliferation, migration and invasion of TE-1 cells and promoted apoptosis. (A) RT-qPCR was used to test the interference efficiency of LINC01711 sh-RNA on TE-1 cells. n=6. (B) The proliferation of TE-1 cells was detected by EdU method. n=6. (C) Colony forming ability was determined by colony formation test. n=6. (D) The apoptosis of TE-1 cells was detected by flow cytometry. (E) The migration of TE-1 cells was detected by wound healing assay. n=6. (F) The invasiveness of TE-1 cells was detected by Transwell method. n=6. (G) Representative tumor images. (H) Tumor volume growth curve of each group, n=5. p < 0.05; ** p < 0.01.