Research Paper Volume 13, Issue 15 pp 19894—19907

Establishing a three-miRNA signature as a prognostic model for colorectal cancer through bioinformatics analysis

The expression levels of miR-21-3p, miR-194-3p and miR-891a-5p in patients with CCa and its correlation with T-stages. The results of RT-qPCR of miR-21-3p’ (A), miR-194-3p’ (B) and miR-891a-5p’ (C) expression levels in colonic cancer cell lines. ***, ** and * represent the remarkable difference compared with NCM460 (PPPD). *** Represent the significant difference compared with adjacent tissues (PE). ***, ** and * represent the significant difference between groups (PPP

Figure 9. The expression levels of miR-21-3p, miR-194-3p and miR-891a-5p in patients with CCa and its correlation with T-stages. The results of RT-qPCR of miR-21-3p’ (A), miR-194-3p’ (B) and miR-891a-5p’ (C) expression levels in colonic cancer cell lines. ***, ** and * represent the remarkable difference compared with NCM460 (P<0.001, P<0.01 and P<0.05), respectively. The expression levels of miR-21-3p, miR-194-3p and miR-891a-5p in carcinoma tissues and adjacent tissues based on the CRC samples of Chongqing University Cancer Hospital Clinical (D). *** Represent the significant difference compared with adjacent tissues (P<0.001). The expression levels of miR-21-3p, miR-194-3p and miR-891a-5p in CCa tissues with various T-stages based on the CRC samples of Chongqing University Cancer Hospital Clinical (E). ***, ** and * represent the significant difference between groups (P<0.001, P<0.01 and P<0.05), respectively.