Research Paper Volume 13, Issue 17 pp 21191—21201

LncRNA PITPNA-AS1 promotes gastric cancer by increasing SOX4 expression via inhibition of miR-92a-3p

The expression of PITPNA-AS1 is upregulated in GC patients. (A) Volcano plot of the lncRNA profile in GC patients tumor and normal adjacent tissues. (B) The expression pattern of PITPNA-AS1 in GC patients tumor and normal adjacent tissues; (C) PITPNA-AS1 expression in MKN-45, SGC7901, and GES-1 cells; (D) dysregulation of PITPNA is related to overall survival in GC patients; (E) dysregulation of PITPNA is related to disease-free survival in GC patients. DFS: Disease-free survival; OS: Overall survival. Data are presented as mean ± SEM. Statistic significant differences were indicated: * P

Figure 1. The expression of PITPNA-AS1 is upregulated in GC patients. (A) Volcano plot of the lncRNA profile in GC patients tumor and normal adjacent tissues. (B) The expression pattern of PITPNA-AS1 in GC patients tumor and normal adjacent tissues; (C) PITPNA-AS1 expression in MKN-45, SGC7901, and GES-1 cells; (D) dysregulation of PITPNA is related to overall survival in GC patients; (E) dysregulation of PITPNA is related to disease-free survival in GC patients. DFS: Disease-free survival; OS: Overall survival. Data are presented as mean ± SEM. Statistic significant differences were indicated: * P < 0.05, ** P < 0.01.