Research Paper Volume 13, Issue 17 pp 21191—21201

LncRNA PITPNA-AS1 promotes gastric cancer by increasing SOX4 expression via inhibition of miR-92a-3p

PITPNA-AS1 interacts with miR-92a-3p to regulate SOX4 expression. (A) SOX4 expression in SGC7901 cells; (B–E) cell proliferation (B), migration (C), invasion (D), and apoptosis (E) in SGC7901 cells containing si-PITPNA-AS1, miR-92a-3p mimic, and SOX4 vector. Data are presented as mean ± SEM. Statistic significant differences were indicated: ** P #P

Figure 5. PITPNA-AS1 interacts with miR-92a-3p to regulate SOX4 expression. (A) SOX4 expression in SGC7901 cells; (BE) cell proliferation (B), migration (C), invasion (D), and apoptosis (E) in SGC7901 cells containing si-PITPNA-AS1, miR-92a-3p mimic, and SOX4 vector. Data are presented as mean ± SEM. Statistic significant differences were indicated: ** P < 0.01 vs. si-NC; #P <0.05 vs.si-PITPNA.