Research Paper Volume 13, Issue 16 pp 20246—20257

Identification of effective natural PIK3CA H1047R inhibitors by computational study

Schematic representation showing intermolecular interactions of predicted binding modes of (A) ZINC000014715656 with PIK3CA H1047R, (B) ZINC000004098448 with PIK3CA H1047R, (C) PKI-402 with PIK3CA H1047R, and (D) wortmannin with PIK3CA H1047R.

Figure 4. Schematic representation showing intermolecular interactions of predicted binding modes of (A) ZINC000014715656 with PIK3CA H1047R, (B) ZINC000004098448 with PIK3CA H1047R, (C) PKI-402 with PIK3CA H1047R, and (D) wortmannin with PIK3CA H1047R.