Research Paper Volume 13, Issue 16 pp 20302—20318

Regulation of follistatin-like 3 expression by miR-486-5p modulates gastric cancer cell proliferation, migration and tumor progression

Elevated FSTL3 expression in gastric cancer is linked to poor patient prognosis. (A) Profiling of FSTL3 expression in 33 cancers within the TCGA database. (B) Analysis of FSTL3 expression in non-cancerous and cancerous gastric tissues using the GEO clinical dataset GSE33335. (C) Kaplan-Meier analysis of gastric cancer patient overall survival after classification into high (red) and low (blue) FSTL3 expression groups (n=175). Significance indicated as follows: *PPP

Figure 1. Elevated FSTL3 expression in gastric cancer is linked to poor patient prognosis. (A) Profiling of FSTL3 expression in 33 cancers within the TCGA database. (B) Analysis of FSTL3 expression in non-cancerous and cancerous gastric tissues using the GEO clinical dataset GSE33335. (C) Kaplan-Meier analysis of gastric cancer patient overall survival after classification into high (red) and low (blue) FSTL3 expression groups (n=175). Significance indicated as follows: *P<0.05, **P<0.01, ***P<0.001.