COVID-19 Research Paper Volume 13, Issue 17 pp 20886—20895

The potential role of abnormal angiotensin-converting enzyme 2 expression correlated with immune infiltration after SARS-CoV-2 infection in the prognosis of breast cancer

Comparison of survival curves of the high and low expression of ACE2 in different subtypes of breast cancer based on immune cells subgroups. For luminal subtype of breast cancer, lower expression level of ACE2 was related to poorer prognosis in enriched CD8+ T cells. The results for HER2 enriched subtype of breast cancer indicated that lower expression of ACE2 was related to poorer prognosis in enriched B cells.

Figure 4. Comparison of survival curves of the high and low expression of ACE2 in different subtypes of breast cancer based on immune cells subgroups. For luminal subtype of breast cancer, lower expression level of ACE2 was related to poorer prognosis in enriched CD8+ T cells. The results for HER2 enriched subtype of breast cancer indicated that lower expression of ACE2 was related to poorer prognosis in enriched B cells.