Research Paper Volume 13, Issue 16 pp 20481—20494

miR-33a-5p inhibits the progression of esophageal cancer through the DKK1-mediated Wnt/β-catenin pathway

Clinical value of miR-33a-5p and DKK1 in esophageal cancer. (A) Expression of miR-33a-5p in esophageal cancer tissues; (B) Serum miR-33a-5p expression in esophageal cancer and ROC curve; (C) Expression of DKK1 in esophageal cancer; (D) Serum DKK1 expression in esophageal cancer and ROC curve; (E) Serum miR-33a-5p expression was correlated with esophageal cancer; (F) Serum DKK1 expression was correlated with the esophageal cancer; (G) Correlation between miR-33a-5p and DKK1 in esophageal cancer tissues; (H) Correlation between miR-33a-5p and DKK1 in serum of esophageal cancer patients; (I) Relationship between serum miR-33a-5p expression and 5-year OS of patients; (J) Relationship between serum DKK1 expression and 5-year OS of patients. The inter-group comparison was conducted by the independent sample t-test, mean ± SD, bP

Figure 1. Clinical value of miR-33a-5p and DKK1 in esophageal cancer. (A) Expression of miR-33a-5p in esophageal cancer tissues; (B) Serum miR-33a-5p expression in esophageal cancer and ROC curve; (C) Expression of DKK1 in esophageal cancer; (D) Serum DKK1 expression in esophageal cancer and ROC curve; (E) Serum miR-33a-5p expression was correlated with esophageal cancer; (F) Serum DKK1 expression was correlated with the esophageal cancer; (G) Correlation between miR-33a-5p and DKK1 in esophageal cancer tissues; (H) Correlation between miR-33a-5p and DKK1 in serum of esophageal cancer patients; (I) Relationship between serum miR-33a-5p expression and 5-year OS of patients; (J) Relationship between serum DKK1 expression and 5-year OS of patients. The inter-group comparison was conducted by the independent sample t-test, mean ± SD, bP < 0.01 for inter-group comparisons.