Research Paper Volume 13, Issue 16 pp 19996—20015

Stress-induced aberrations in sensory processing predict worse cognitive outcomes in healthy aging adults

Time-domain response to electrical stimulation. (Left): Time domain average of data from a representative sensor near the left sensorimotor cortex (M0443). Grand-averaged sLORETA source estimates (inset in top right) of statistically-derived sensor-level temporal clusters showed robust increases in phase-locked neural activity from 25-125 ms and 525-625 ms in the left primary somatosensory cortex. (Right): The peak voxel time course revealed significantly attenuated time-domain responses to the second stimulation compared to the first, indicative of significant gating of time-domain activity across all participants during paired-pulse stimulation (Right: box plot). ***p

Figure 3. Time-domain response to electrical stimulation. (Left): Time domain average of data from a representative sensor near the left sensorimotor cortex (M0443). Grand-averaged sLORETA source estimates (inset in top right) of statistically-derived sensor-level temporal clusters showed robust increases in phase-locked neural activity from 25-125 ms and 525-625 ms in the left primary somatosensory cortex. (Right): The peak voxel time course revealed significantly attenuated time-domain responses to the second stimulation compared to the first, indicative of significant gating of time-domain activity across all participants during paired-pulse stimulation (Right: box plot). ***p < .001.