Research Paper Volume 13, Issue 17 pp 21283—21293

RUFY3 promotes the progression of hepatocellular carcinoma through activating NF-κB-mediated epithelial-mesenchymal transition

NF-κB signaling involved in RUFY3-induced HCC cell EMT, growth, migration, and invasion. (A) Western blot analysis of the levels of p-NF-κB p65, E-cadherin and N-cadherin in modified SMMC7721 cell treated with helenalin. (B) CCK-8 analysis of cell proliferation ability in modified SMMC7721 cell treated with helenalin. (C) Determination of cell migration and invasion abilities in modified SMMC7721 cell treated with helenalin. *P

Figure 6. NF-κB signaling involved in RUFY3-induced HCC cell EMT, growth, migration, and invasion. (A) Western blot analysis of the levels of p-NF-κB p65, E-cadherin and N-cadherin in modified SMMC7721 cell treated with helenalin. (B) CCK-8 analysis of cell proliferation ability in modified SMMC7721 cell treated with helenalin. (C) Determination of cell migration and invasion abilities in modified SMMC7721 cell treated with helenalin. *P<0.05.