Research Paper Volume 13, Issue 16 pp 20661—20683

METTL21B is a prognostic biomarker and potential therapeutic target in low-grade gliomas

Association between METTL21B and immune infiltration. (A) Infiltration levels of all six immune cell types were significantly positively correlated with expression of METTL21B in LGG by TIMER. (B) Immune scores between low and high METTL21B expression group. (C) Multivariate Cox model for infiltration of six immune cell types and METTL21B expression. (D) Distribution of 22 subtypes of immune cells in all TCGA-LGG samples. (E) Infiltration levels of 22 subtypes of immune cells between low and high METTL21B expression group in LGG. *P

Figure 7. Association between METTL21B and immune infiltration. (A) Infiltration levels of all six immune cell types were significantly positively correlated with expression of METTL21B in LGG by TIMER. (B) Immune scores between low and high METTL21B expression group. (C) Multivariate Cox model for infiltration of six immune cell types and METTL21B expression. (D) Distribution of 22 subtypes of immune cells in all TCGA-LGG samples. (E) Infiltration levels of 22 subtypes of immune cells between low and high METTL21B expression group in LGG. *P<0.05; **P<0.01; ***P<0.001; ****P<0.0001; ns: no significance.