Research Paper Volume 13, Issue 16 pp 20738—20747

Apatinib inhibits the proliferation of gastric cancer cells via the AKT/GSK signaling pathway in vivo

Proliferation of zebrafish xenograft model inhibited by apatinib treatment. (A) Fluorescence image of tumor size in zebrafish induced by MGC-803 with/without apatinib treatment at 1, 2 and 3 dpt. Scale bar: 200 μm. (B) Quantitative analysis of the length of MGC-803 cells proliferation in zebrafish with/without apatinib treatment. Dpt: days post treatment.

Figure 4. Proliferation of zebrafish xenograft model inhibited by apatinib treatment. (A) Fluorescence image of tumor size in zebrafish induced by MGC-803 with/without apatinib treatment at 1, 2 and 3 dpt. Scale bar: 200 μm. (B) Quantitative analysis of the length of MGC-803 cells proliferation in zebrafish with/without apatinib treatment. Dpt: days post treatment.