Research Paper Volume 13, Issue 20 pp 23579—23587

AHNAK suppresses ovarian cancer progression through the Wnt/β-catenin signaling pathway

Elevated AHNAK content suppresses ovarian cancer tumor growth along with migration in vivo. (A) The tumors from the mouse xenograft model (n = 3 per group) are shown (left). The weights of the tumors are summarized (right). (B) HE-stained sections derived from lung metastatic nodules of the mouse xenograft model (n = 3 per group) are illustrated (left). The number of lung nodules was quantified (right). Original magnification: 40X and 200X, **P

Figure 3. Elevated AHNAK content suppresses ovarian cancer tumor growth along with migration in vivo. (A) The tumors from the mouse xenograft model (n = 3 per group) are shown (left). The weights of the tumors are summarized (right). (B) HE-stained sections derived from lung metastatic nodules of the mouse xenograft model (n = 3 per group) are illustrated (left). The number of lung nodules was quantified (right). Original magnification: 40X and 200X, **P < 0.01.