Research Paper Volume 13, Issue 16 pp 20808—20819

LINC01087 inhibits glioma cell proliferation and migration, and increases cell apoptosis via miR-384/Bcl-2 axis

LINC01087 regulates miR-384/Bcl-2 to take part in the proliferation and apoptosis of glioma. (A) qRT-PCR detected the relative expression levels of Bcl-2, LINC01087, and miR-384 in cells after co-transfection. (B) Proliferation of glioma cells after co-transfection was tested by CCK-8. (C) The changes of cloning of glioma cells after co-transfection were detected by cloning experiment. (D) The apoptosis rate of glioma cells after co-transfection was tested by flow cytometry. (E) The relative caspase-3 activity was measured by the caspase-3 activity kit. (*P **P

Figure 5. LINC01087 regulates miR-384/Bcl-2 to take part in the proliferation and apoptosis of glioma. (A) qRT-PCR detected the relative expression levels of Bcl-2, LINC01087, and miR-384 in cells after co-transfection. (B) Proliferation of glioma cells after co-transfection was tested by CCK-8. (C) The changes of cloning of glioma cells after co-transfection were detected by cloning experiment. (D) The apoptosis rate of glioma cells after co-transfection was tested by flow cytometry. (E) The relative caspase-3 activity was measured by the caspase-3 activity kit. (*P < 0.05, **P < 0.01).