Research Paper Advance Articles

Low expression of KIF20A suppresses cell proliferation, promotes chemosensitivity and is associated with better prognosis in HCC

Effects of KIF20A knockdown on the HCC cell proliferation and capsase-3 and -9 activities. (A) qRT-PCR analysis of KIF20A mRNA expression in LO2, HepG2 and SK-Hep1 cells. (B, C) qRT-PCR analysis of KIF20A mRNA expression level in HepG2 (B) and SK-Hep1 cells (C) transfected with si-NC or si-KIF20A. (D, E) MTS assay analysis of cell proliferation of HepG2 (D) and SK-Hep1 cells (E) transfected with si-NC or si-KIF20A. (F, G) Capsase-3 activity analysis of caspase-3 activities of HepG2 (F) and SK-Hep1 cells (G) transfected with si-NC or si-KIF20A. (H, I) Capsase-9 activity analysis of caspase-9 activities of HepG2 (H) and SK-Hep1 cells (I) transfected with si-NC or si-KIF20A.

Figure 7. Effects of KIF20A knockdown on the HCC cell proliferation and capsase-3 and -9 activities. (A) qRT-PCR analysis of KIF20A mRNA expression in LO2, HepG2 and SK-Hep1 cells. (B, C) qRT-PCR analysis of KIF20A mRNA expression level in HepG2 (B) and SK-Hep1 cells (C) transfected with si-NC or si-KIF20A. (D, E) MTS assay analysis of cell proliferation of HepG2 (D) and SK-Hep1 cells (E) transfected with si-NC or si-KIF20A. (F, G) Capsase-3 activity analysis of caspase-3 activities of HepG2 (F) and SK-Hep1 cells (G) transfected with si-NC or si-KIF20A. (H, I) Capsase-9 activity analysis of caspase-9 activities of HepG2 (H) and SK-Hep1 cells (I) transfected with si-NC or si-KIF20A.