Research Paper Volume 13, Issue 17 pp 21571—21586

TNFSF9 promotes metastasis of pancreatic cancer through Wnt/Snail signaling and M2 polarization of macrophages

TNFSF9 promotes metastasis of pancreatic cancer in vivo. (A) Compared with the sh-TNFSF9 group, there were obvious metastases in the liver tissue of nude mice in the sh-NC group, and no normal spleen tissue was seen. (B) HE staining confirmed liver metastases of pancreatic cancer and splenic implants. The red arrow indicates metastasis of liver lesions. The blue arrow indicates the spleen implanted tumor.

Figure 7. TNFSF9 promotes metastasis of pancreatic cancer in vivo. (A) Compared with the sh-TNFSF9 group, there were obvious metastases in the liver tissue of nude mice in the sh-NC group, and no normal spleen tissue was seen. (B) HE staining confirmed liver metastases of pancreatic cancer and splenic implants. The red arrow indicates metastasis of liver lesions. The blue arrow indicates the spleen implanted tumor.