Research Paper Volume 13, Issue 17 pp 21029—21039

Familial longevity is associated with lower baseline bone turnover but not differences in bone turnover in response to rhTSH

Bone resorption (CTX) and bone formation (P1NP) markers in offspring versus controls at baseline of rhTSH study. (A) Mean CTX at baseline of rhTSH study in offspring (n = 14) and controls (n = 12), p value B) Mean P1NP at baseline of rhTSH study in offspring (n = 14) and controls (n = 12), p value P value

Figure 2. Bone resorption (CTX) and bone formation (P1NP) markers in offspring versus controls at baseline of rhTSH study. (A) Mean CTX at baseline of rhTSH study in offspring (n = 14) and controls (n = 12), p value <0.01. (B) Mean P1NP at baseline of rhTSH study in offspring (n = 14) and controls (n = 12), p value <0.01. Abbreviations: rhTSH: recombinant human thyroid stimulating hormone; CTX: collagen type 1 C-terminal cross-linked telopeptide (CTX); P1NP: N-terminal propeptide of type 1 collagen. Error bars: standard error of the mean. P value <0.05 was considered statistically significant.