Research Paper Volume 13, Issue 17 pp 21729—21742

Cytokine antibody array-based analysis of IL-37 treatment effects in asthma

Correlations of IL-37 levels with clinical characteristics. Each points represents one person. (A) There is no correlation between IL-37 mRNA levels and % sputum eosinophils (r=-0.28, p=0.30). (B) There is no correlation between IL-37 mRNA levels and % peripheral blood eosinophils (r=-0.40, p=0.09). (C) There is no correlation between IL-37 mRNA levels and %FEV1/FVC (r=-0.10, p=0.74). (D) There is no correlation between IL-37 mRNA levels and peripheral blood IgE (r=-0.44, p=0.14). (E) ACT-scores were negatively correlated with IL-37 mRNA levels (r=-0.74, p=0.04). (F) There is no correlation between IL-37 mRNA levels and mini-AQLQ-scores (r=-0.28, p=0.30). Data were analyzed using Spearman’s rank correlation.

Figure 2. Correlations of IL-37 levels with clinical characteristics. Each points represents one person. (A) There is no correlation between IL-37 mRNA levels and % sputum eosinophils (r=-0.28, p=0.30). (B) There is no correlation between IL-37 mRNA levels and % peripheral blood eosinophils (r=-0.40, p=0.09). (C) There is no correlation between IL-37 mRNA levels and %FEV1/FVC (r=-0.10, p=0.74). (D) There is no correlation between IL-37 mRNA levels and peripheral blood IgE (r=-0.44, p=0.14). (E) ACT-scores were negatively correlated with IL-37 mRNA levels (r=-0.74, p=0.04). (F) There is no correlation between IL-37 mRNA levels and mini-AQLQ-scores (r=-0.28, p=0.30). Data were analyzed using Spearman’s rank correlation.