Figure 1. HCG11 expression is decreased in OS and closely related to clinical factors. (A) HCG11 expression in OS tissues and ANTs was analyzed by qRT-PCR. (B) The ratio of relative HCG11 expression in OS tissues versus ANTs shown on the logarithmic scale. (C) HCG11 expression in OS cell lines (MG63, HOS, Saos-2, U2OS and 143B) and human osteoblast cell line (hFOB1.19) was analyzed by qRT-PCR. (D) HCG11 level in tumors ≥ 5cm and < 5cm was compared. (E) Overall survival of OS patients was analyzed by the Kaplan-Meier method. **P < 0.01, ***P < 0.001.