Research Paper Volume 13, Issue 18 pp 22332—22344

METTL3-mediated m6A modification of KIF3C-mRNA promotes prostate cancer progression and is negatively regulated by miR-320d

KIF3C silence prevented the proliferation of PC cells in vivo. (A) Represent image of nude mouse tumors (n=5). (B) The implanted tumor volume of the KIF3C knockdown PCa cells nude mouse. (C) The implanted tumor weight of the KIF3C knockdown PCa cells nude mouse. (D) Typical IHC staining images showing Ki-67, PCNA and KIF3C of the implanted tumors. Data are reported as means ± standard deviation of three independent experiments. *p

Figure 6. KIF3C silence prevented the proliferation of PC cells in vivo. (A) Represent image of nude mouse tumors (n=5). (B) The implanted tumor volume of the KIF3C knockdown PCa cells nude mouse. (C) The implanted tumor weight of the KIF3C knockdown PCa cells nude mouse. (D) Typical IHC staining images showing Ki-67, PCNA and KIF3C of the implanted tumors. Data are reported as means ± standard deviation of three independent experiments. *p < 0.05; **p < 0.01.