Research Paper Volume 13, Issue 18 pp 22390—22411

Deficiency of miR-29b2/c leads to accelerated aging and neuroprotection in MPTP-induced Parkinson’s disease mice

The muscle weakness and gait abnormality in miR-29b2/c KO mice. (A) The results of the Wire hanging test in WT and miR-29b2/c KO mice. n=12-14. (B) The results of Grid hanging test in WT and miR-29b2/c KO mice. n=6-13. (C) The results of Rotarod test in WT and miR-29b2/c KO mice. n=12-24. (D) The results of Catwalk test in WT and miR-29b2/c KO mice. n=12-21. The differences were analyzed by Student-T-test. *P P P P

Figure 2. The muscle weakness and gait abnormality in miR-29b2/c KO mice. (A) The results of the Wire hanging test in WT and miR-29b2/c KO mice. n=12-14. (B) The results of Grid hanging test in WT and miR-29b2/c KO mice. n=6-13. (C) The results of Rotarod test in WT and miR-29b2/c KO mice. n=12-24. (D) The results of Catwalk test in WT and miR-29b2/c KO mice. n=12-21. The differences were analyzed by Student-T-test. *P < 0.05, **P < 0.01, ***P < 0.001 and ****P < 0.0001.